Using Laxatives For Taking Care Of Constipation
Most people who suffer from constipation manage a type known as functional or idiopathic constipation. This type of constipation is so called because the underlying cause is not identifiable, yet the condition can be easy diagnosed due to the symptoms. Treatment at first consists of increased dietary fiber. If this is ineffective, patients are recommended to try a laxative.
There seems to be widespread agreement among scientists and doctors that the judicious use of laxative constipation treatments is tolerated and safe. However, as some patients take such medications over extended periods, suspicions have surfaced about long-term side effects and problems. A result of these suspicions are some misconceptions about laxative use.
There are three kinds of misconceptions about laxative usage. The first is the idea that long term use causes nerves in the gastrointestinal tract to be damaged. The second is the idea that long term use leads to higher chance of cancer. The third is that the gut starts to become “immune” to laxatives and perhaps suffer “rebound” effects that worsen constipation.
With respect to the first, reports first surfaced in studies on patients who had been using laxative constipation treatments for a long term. Studies of the colonic lining showed a discoloration. Follow-up showed that some had nerve damage. THe problem is that these studies were not well controlled with a placebo population. Critics say that patients with constipation already have higher predisposition to nerve damage. Later studies did not hold up the causal link between constipation medication and laxatives.
On the topic of the second, people reported a connection from laxatives to cancer by looking at animal experimentation. Rodents which were given very high doses of laxatives showed more DNA damage and thus propensity toward cancer. Yet the studies used extremely high concentrations of drugs that are never seen in humans. Likewise, studies with such high concentrations of aspartame and artificial sweeteners show a link between consumption and cancer that are rarely realized in epidemiological surveys.
On the topic of the third, informal reports from patients who said they were seeing diminished effectiveness from medication initiated the idea of laxative intolerance. The counterpoint to this is that controlled studies in both animals and quadraplegic patients who used laxatives for as long as 34 years did not suffer from intolerance effects.
Laxatives seem to be a helpful part of the treatment regimen to combat constipation. The reports of these three kinds of side effects needs to evaluated against case studies which show the opposite: that long term side-effects are not a given.
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